CBD Claims with Clinical Studies

Dr. Bonni Goldstein, Cannabis physician: Pain from inflammation can and will affect all adults at some point in their lives, and for some, become chronic and interfere with a normal quality of life. Multiple studies have proven the anti-inflammatory benefits of phytocannabinoids and terpenoids, the compounds that abound in the cannabis plant. (Pertwee, 1999, Klein 2005, Nagarkatti 2009, Booz, 2011, Xiong 2012, Mecha 2013).

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The plant cannabinoids have many different mechanisms of action in their anti-inflammatory properties, including the blockage of pro-inflammatory compounds that are made in the body as a result of injury or illness. CBDA, cannabidiolic acid, the raw non-psychoactive cannabinoid precursor to CBD, showed significant COX-2 enzyme blockage when compared to placebo, two NSAIDs and other cannabinoids. (Takeda 2008).

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Dr. Ethan Russo and Dr. Geoffrey Guy, in their excellent 2005 study, report that the phytocanna- binoids work synergistically (the “entourage effect”) to provide balanced and nontoxic medicinal effects when compared with single molecule anti-inflammatories. (Russo and Guy, 2005).